“Soham Chanda, an assistant professor in the Department of Biochemistry and Molecular Biology, has designed a new experimental system that can rapidly assess the pathogenic effects of a drug on a baby’s developing brain. His system uses embryonic stem cells reprogrammed into neurons, offering a powerful tool for probing genetic and molecular underpinnings of drug-induced neurodevelopmental disorders. The knowledge gained from this new method could be harnessed to uncover unknown drug risks, as well as preventive therapies.
The research is published in Cell Stem Cell, and the work was primarily carried out while Chanda was a postdoctoral researcher at Stanford University with Thomas Südhof and Marius Wernig. Chanda joined the Colorado State University faculty in January and is continuing to devise methods for understanding biochemical properties of early-stage neuronal development as one of his key research interests.”