Earlier Detection of Ruminant Pregnancy


Available for Licensing

IP Status

US Utility Patent: US 9933437
US Utility Patent: US 10288625


Thomas R Hansen
Jared J Romero
Torrance M Nett
Jessica Prenni
Kevin McSweeney
Fuller W Bazer
Alfredo Q Antoniazzi

At A Glance

Researchers at Colorado State University have developed a patented sensitive radioimmunoassay (RIA) for bovine and ovine interferon tau (IFNT) to determine pregnancy 14 days earlier than industry standard.

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Licensing Director

Steve Foster

Reference No.:  14-016


The current gold standard for determining pregnancy status in cattle is through rectal ultrasound on day 32 of predicted/possible pregnancy. By completing the patented RIA for IFNT on Day 18, accurately determining pregnancy status, it is possible to make re-breeding decisions for non-pregnant cows 14 days earlier – having great economic impact for dairy and beef cattle operations.

  • IFNT is only produced by the trophectoderm cells of the ruminant embryo
  • Lack of detection of IFNT is key in managing ruminant reproductive cycles

Hansen, Thomas R, et al. “Paracrine and Endocrine Actions of Interferon Tau (IFNT) in: Reproduction Volume 154 Issue 5 (2017).” Reproduction, Bioscientifica Ltd, 16 Apr. 2019, rep.bioscientifica.com/view/journals/rep/154/5/REP-17-0315.xml.

Romero, Jared Jerome. “Endocrine Actions of IFNT during Early Ruminant Pregnancy.” Mountain Scholar Home, Colorado State University. Libraries, 2013, mountainscholar.org/handle/10217/80972.

Last updated: April 2020

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