Enhancement of Bioprocess Product Yields

Method of Increasing the Efficiency of the Conversion of Sugars and Other Substrates to Products of Microbial Cultivations

Available for Licensing

IP Status

US Utility Patent Pending (Not Yet Published)


Kenneth Reardon
Xingfeng Huang

At A Glance

To increase conversion efficiency, researchers at Colorado State University developed two approaches:  cell immobilization and the addition of growth-inhibitory compounds.  Ethanol production from anaerobic fermentation of a hydrolyzed form of algal biomass resulted in an increase of 20%.  Similar results for other yeast species growing on other biomass hydrolysates or carbon sources in anaerobic fermentation can be expected.

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Licensing Director

Mandana Ashouri

Reference No.:  2019-122


Ethanol and other metabolic products derived from the cultivation of microorganisms form the backbone of industrial biotechnology. With increased interest in sustainability and the move to find replacements for petroleum-derived chemicals, the production of bio-based chemicals is expected to increase substantially over the coming decade.  One factor limiting the environmental and economic sustainability of these bioprocesses is the production of cellular biomass by the microorganisms, which de facto reduces the conversion of carbon from the feed (substrate) molecules, typical sugars, to the desired product.

  • Improved economic and environmental sustainability metrics

Last updated: April 2020

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