Inactivation of Viral Particles and Other Pathogens Using Bulk Sterilization
Opportunity
Available for Licensing, Collaboration, and Funding
IP Status
US Utility Patent Pending (Not Yet Published)
Inventors
Bryan D. Willson
John C. Mizia
Raymond P. Goodrich
At A Glance
Researchers at Colorado State University have developed compositions, methods, and apparatus for inactivating infectious disease pathogens, including the COVID-19 virus, by exploiting the unique property of the photosensitizer riboflavin and UV light to selectively inactivate bacteria and viruses by directed damage to nucleic acids. The nature of the photosensitizer (riboflavin) provides for low toxicity and thus easy handling, distribution and processing even under austere conditions.
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Background
Riboflavin, or vitamin B2, is a naturally occurring compound and an essential human nutrient. Studies have demonstrated that riboflavin, when exposed to visible or UV light, may be used to inactivate pathogens. In addition, the antimicrobial activity of UV irradiation includes sporicidal and virucidal effects. The ability to exploit these process has proven effective against a wide range of pathogens.
Benefits
- Photochemical, riboflavin, is inexpensive, non-toxic, and does not pose safety or environmental concerns
Applications
- Disinfect a wide variety of substances, surfaces, equipment, etc.
Last updated: April 2020