Susan P. James, PhD

Professor, Mechanical Engineering and Biomedical Engineering

Startup Company
Why I Commercialize

“I think that people who are innovative and creative very often go into performance and music arts.  I actually wanted to be an artist, but the practical side of my brain and my pocketbook won out, and I decided to be an engineer instead.  I was so happy when I discovered how engineering must be creative to solve practical problems.

I always tell folks that if they’re going to join my group, they must be willing to focus on solving specific applied problems – we are creating solutions to real-world medical problems.  We are trying to get our solutions into the clinic. It’s not that I don’t like basic science; I depend on basic science. I stand on the shoulders of giants – once we get the Innovation going and we know it is working, we can then ask the basic science questions to understand why it works so we  can make it even better.

You don’t get into commercialization because you think you’re going to make a lot of money from your technology.  We do it because we want to make a difference, and we want to transfer our scholarship to the real world.  Our goal is to get our inventions into people as safely and effectively, and as quickly as as we can do it safely and effectively.

Yes, it is nice to get a royalty check once in awhile, especially when you have a nice pot of royalty money to support future research.  I got first hand experience seeing that as I got my PhD in a lab that was very inventive, and was highly successful in commercializing innovations for hip replacements.  I got to see what having that royalty income does for research; having discretionary money is really good for innovation and creativity as you can try things that are not typically funded by NIH grants.”

Areas of Collaborative Interest

My lab makes biomaterials that go into the body for one reason or another, usually as implants or for regeneration or monitoring. I used to do a lot of work in the orthopedic industry; currently, we are working on polymeric leaflet heart valves.  Our technology is really quite unique – it it has the durability of a mechanical heart valve and the blood friendliness of a tissue valve, and it’s a lot cheaper than tissue valves.  We can also make them any size and any shape, which you cannot do when working with animal tissue.  We have completed years of deliberate research into the technology in a more diligent way than a company can.

There are more heart valve patients in India than anywhere in the world and most of them could not afford to the kind of the real expensive heart valves that are on the market right now.  Our technologies are more affordable than the current standards, which could improve access to treatment options for those who cannot afford tissue-based heart valves.  This has lead to our collaboration with a leader in the heart valve field, Lakshmi Prasad Dasi, helping to optimize this technology.

I am interested in collaborating in the following areas:

  • licensing our technologies
Selected Issued Patents
  • US 10,435,523 B2:  Material comprising outer layer having entanglement of hydrophobic polymer host blended with anhydride functionalized hydrophobic polymer co-host and hydrophilic guest
  • US 10,266,684 B2, IN2014DN07588A::  Glycosaminoglycan and Synthetic Polymer Material for Blood-Containing Applications
  • US 10,265,440 B2, EP 2 493 942 B1: Polymeric Materials Including a Glycosaminoglycan Networked with a Polyolefin-Containing Polymer
  • US 10,167,387 B2, EP 3 044 250 A1: Synthetic Polymeric Materials and Devices Thereof
  • US 10,071,186 B2, EP 2 825 203 A1, NZ629494A  Glycosaminoglycan and Synthetic Polymer Material for Blood-Containing Applications
  • US 09,533,077 B2, CA2721924C:  Outer layer having entanglement of hydrophobic polymer host blended with a maleated hydrophobic polymer co-host, and hydrophilic polymer guest
  • US 09,567.447 B2:  Outer Layer Having Entanglement of Hydrophobic Polymer Host and Hydrophilic Polymer Guest
  • US 08,524,886 B2:  Outer layer having entanglement of hydrophobic polymer host and hydrophilic polymer guest
  • US 08,524,884 B2, EP 2 283 065 B1:  Outer Layer Material Having Entanglement of Hydrophobic Polymer Host Blended with a Maleated Hydrophobic Polymer Co-Host, and Hydrophilic Polymer Guest
  • US 08,133,168 B2:  Remediation of Functional Cardiac Mitral Valve Regurgitation
  • US 07,692,000 B2:  Hyaluronan (HA) Esterification via Acylation Technique for Moldable Devices
  • US 07,662,954 B2:  Outer Layer Having Entanglement of Hydrophobic Polymer Host and Hydrophilic Polymer Guest
  • US 07,120,258 B1:  Apparatus and Methods for Mitigating Impairments Due to Central Auditory Nervous System Binaural Phase-Time Asynchrony*
  • US 05,480,450 A: Method and Apparatus for Reducing Interfacial Porosity in a Cemented Femoral Prosthesis*
  • EP 2 146 737 A1:  Copolymer Synthesized from a Modified Glycosaminoglycan (GAG) and an Anhydride Functionalized Hydrophobic Polymer
    *Assignee other than Colorado State University Research Foundation
Patent list generated using Google Patents; Last updated on October 1, 2019.
Hidden text – because the “design” is “light” text:

Sue James, Susan P. James, Susan James

#CSUInvents – Inventor Highlight! Professor SUSAN JAMES and the team in the #Biomaterials Research and #Engineering Lab in the CSU Walter Scott, Jr. College of Engineering focus on the development and characterization of biomaterials for #cardiovascular and #orthopedic health care. Learn more about Dr. James as an #inventor, her #technologies, and BioPoly LLC.

#innovation #patents #cardiology #polymers #medicaldevices #medtech