Systems and Methods for Manufacturing Customized Cardiovascular Devices

Unaltered Image by BMJ Research: BMJ 2013;347:f6499

Available for Licensing

IP Status

PCT Patent Pending: WO 2018/144462


David A Prawel
Susan P James
Ashley L Beckwith

At A Glance

Researchers at Colorado State University have developed systems and methods for manufacturing customized cardiovascular devices using 3D printed thermo-plastic urethane (TPU).

For more information, please contact our office.

Licensing Director

Steve Foster

Reference No.:  15-033


Heart disease remains a leading cause of death in the United States and globally, with people of all ages and backgrounds being susceptible to the condition in various forms.  Cardiovascular devices may be surgically implanted in a patient to repair, replace, or otherwise provide therapy for damaged cardiovascular anatomy.  Patients suffering from aortic stenosis or similar heart valve diseases may undergo surgery to replace a defective heart valve with a prosthetic valve.  Whereas a stent may be placed in a narrow or blocked artery during a percutaneous coronary intervention to restore blood flow.  Such cardiovascular devices are typically challenging to manufacture.  Furthermore, due to manufacturing constraints, many conventional cardiovascular devices are difficult to fit within the patient anatomical structures during a surgical procedure and/or are prone to reduced operability to provide effective therapy within the environment of the patient anatomy.  Often, conventional cardiovascular devices fail to account for patient-specific morphologies and surgical approaches.

  • Custom, patient specific heart valves
  • Better performing (especially with custom shape engineering)
  • Lower thrombogenesis with HA-enhancement
  • Custom engineered surface features – manages blood flow, vortex generation, turbulence

Last updated: May 2020

Add keywords or various names of inventors here (text is hidden)